Who needs a traditional round of “Happy Birthday” when you’ve got the Queen of Pop trying one of your biggest smashes on for size?!

In Miami on December 2 — Britney Spears‘s birthday — Madonna hosted a benefit for Malawi that raked in $7.5 million (!) for the cause. The guest list was star-studded, and that made for plenty of memorable moments, which included a smooch between Madge and Ariana Grande and a bit involving Sean Penn and handcuffs (but in an intentionally silly way, not a Oh Geez What Did Sean Penn Do At This Fancy Party way).

Still, that’s nothing compared to Madonna’s woozy, slowed-way-down version of “Toxic,” which made for a Tim Burton-esque rendition of the 2003 smash audience members won’t be forgetting anytime soon.

Those cries of “YES, BITCH!” were drowned out by the chorus, as the crowd started singing along by the time Madonna started “slippin’ under.” Even if the song sounded completely different at Art Basel, everyone could recognize that hook and croon along with it.

Needless to say, Madonna definitely knows how to throw a party, surprises, shenanigans and all.

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